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The Oral Semaglutide Treatment Effect in People with Obesity (OASIS) study was implemented in individuals with obesity or overweight associated with comorbidities comparing oral SMG (n = 320) versus placebo (n = 307) over 68 weeks [150]
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One trial showed that two-thirds of patients on once-weekly semaglutide 2.4 mg (Wegovy, Novo Nordisk) regained their weight 1 year after stopping the medication
